HBV Target gene Detail Information

> DEFB103B Gene Search Result

Gene Information

Gene Name	DEFB103B
Gene ID	55894
Gene Full Name	defensin beta 103B
Gene Alias	BD-3; HBD3; HBP3; DEFB3; HBD-3; HBP-3; DEFB-3; DEFB103
Transcripts	ENSG00000177243
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Predicted secreted proteins, Transporters
Uniport_ID	P81534
HGNC ID	HGNC:31702
VEGA ID	OTTHUMG00000189978
OMIM ID	606611
String ID	9606.ENSP00000324633
PharmGKB ID	PA134933952

Target gene [DEFB103B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1401587	chr8	8			8	View
1401588	chr8	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of DEFB103B expression and immune infiltrating cell level correlation result in HBV+ samples
DEFB103B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).