Home
Virus
Gene
Disease
Dataset
Download
Help
 
HBV Target gene Detail Information

> DEFA1B Gene Search Result


Gene Information
Gene Name DEFA1B
Gene ID 728358
Gene Full Name defensin alpha 1B
Gene Alias HP1; HP-1; HNP-1
Transcripts ENSG00000285176
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters
Uniport_ID P59665
HGNC ID HGNC:33596
VEGA ID OTTHUMG00000149850
String ID 9606.ENSP00000372136
PharmGKB ID PA165585475
Target gene [DEFA1B] related to VISs
DVIDChromosomeHMTFBSCASum of Overlapped RecordsDetail
1403463 chr8 25 25 View
Showing 1 to 1 of 1 entries
FirstPrevious1NextLast

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DEFA1B expression and immune infiltrating cell level correlation result in HBV+ samples
DEFA1B expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).