HIV Target gene Detail Information

> DEDD Gene Search Result

Gene Information

Gene Name	DEDD
Gene ID	9191
Gene Full Name	death effector domain containing
Gene Alias	DEFT; KE05; DEDD1; FLDED1; CASP8IP1
Transcripts	ENSG00000158796
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	O75618
HGNC ID	HGNC:2755
VEGA ID	OTTHUMG00000033104
OMIM ID	606841
String ID	9606.ENSP00000356985
PharmGKB ID	PA27236

Target gene [DEDD] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4009192	chr1	12			12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DEDD expression and immune infiltrating cell level correlation result in HIV+ samples
DEDD expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DEDD expression and immune infiltrating cell level correlation result in HIV+ samples
DEDD expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).