HBV Target gene Detail Information

> DDB1 Gene Search Result


Gene Information
Gene Name DDB1
Gene ID 1642
Gene Full Name damage specific DNA binding protein 1
Gene Alias XPE; DDBA; XAP1; XPCE; XPE-BF; UV-DDB1
Transcripts ENSG00000167986
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID Q16531
HGNC ID HGNC:2717
VEGA ID OTTHUMG00000168209
OMIM ID 600045
String ID 9606.ENSP00000301764
PharmGKB ID PA27187
Target gene [DDB1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1014071 chr11 3 1 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DDB1 expression and immune infiltrating cell level correlation result in HBV+ samples
DDB1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).