HIV Target gene Detail Information

> DCUN1D2 Gene Search Result

Gene Information

Gene Name	DCUN1D2
Gene ID	55208
Gene Full Name	defective in cullin neddylation 1 domain containing 2
Gene Alias	C13orf17
Transcripts	ENSG00000150401
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q6PH85
HGNC ID	HGNC:20328
VEGA ID	OTTHUMG00000017390
String ID	9606.ENSP00000417706
PharmGKB ID	PA134941036

Target gene [DCUN1D2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007496	chr13	6	12	1	19	View
4007708	chr13	18			18	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of DCUN1D2 expression and immune infiltrating cell level correlation result in HIV+ samples
DCUN1D2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of DCUN1D2 expression and immune infiltrating cell level correlation result in HIV+ samples
DCUN1D2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).