HBV Target gene Detail Information

> DCT Gene Search Result

Gene Information

Gene Name	DCT
Gene ID	1638
Gene Full Name	dopachrome tautomerase
Gene Alias	TRP-2; TYRP2
Transcripts	ENSG00000080166
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted membrane proteins
Uniport_ID	P40126
HGNC ID	HGNC:2709
VEGA ID	OTTHUMG00000017206
OMIM ID	191275
String ID	9606.ENSP00000392762
PharmGKB ID	PA27179

Target gene [DCT] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005029	chr13	14	8	41	63	View
1402298	chr13	14	8	41	63	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of DCT expression and immune infiltrating cell level correlation result in HBV+ samples
DCT expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).