HTLV1 Target gene Detail Information

> DCLK2 Gene Search Result

Gene Information

Gene Name	DCLK2
Gene ID	166614
Gene Full Name	doublecortin like kinase 2
Gene Alias	CL2; DCK2; CLIK2; DCDC3; CLICK2; DCDC3B; DCAMKL2; CLICK-II
Transcripts	ENSG00000170390
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, Predicted intracellular proteins
Uniport_ID	Q8N568
HGNC ID	HGNC:19002
VEGA ID	OTTHUMG00000161444
OMIM ID	613166
String ID	9606.ENSP00000303887
Drugbank ID	BE0009384
PharmGKB ID	PA162383366

Target gene [DCLK2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6006514	chr4	38	16	13	67	View
6018178	chr4	9			9	View
6023053	chr4	4			4	View
6024968	chr4	3			3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of DCLK2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
DCLK2 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of DCLK2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
DCLK2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).