HBV Target gene Detail Information

> DCDC1 Gene Search Result


Gene Information
Gene Name DCDC1
Gene ID 341019
Gene Full Name doublecortin domain containing 1
Gene Alias DCDC5
Transcripts ENSG00000170959
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Cancer-related genes, Predicted intracellular proteins
Uniport_ID P59894
HGNC ID HGNC:20625
VEGA ID OTTHUMG00000150144
OMIM ID 608062
String ID 9606.ENSP00000385936
PharmGKB ID PA134970075
Target gene [DCDC1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1012933 chr11 2 4 6 View
1018362 chr11 0 View
1400293 chr11 4 1 5 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DCDC1 expression and immune infiltrating cell level correlation result in HBV+ samples
DCDC1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).