HBV Target gene Detail Information

> DCAF8 Gene Search Result


Gene Information
Gene Name DCAF8
Gene ID 50717
Gene Full Name DDB1 and CUL4 associated factor 8
Gene Alias GAN2; H326; WDR42A
Transcripts ENSG00000132716
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Cytosol;
HPA Protein Class Info Disease related genes, Predicted intracellular proteins
Uniport_ID Q5TAQ9
HGNC ID HGNC:24891
VEGA ID OTTHUMG00000031604
OMIM ID 615820
PharmGKB ID PA165751195
Target gene [DCAF8] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1006715 chr1 35 35 View
1400166 chr1 3 1 4 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DCAF8 expression and immune infiltrating cell level correlation result in HBV+ samples
DCAF8 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).