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HIV Target gene Detail Information

> DCAF6 Gene Search Result


Gene Information
Gene Name DCAF6
Gene ID 55827
Gene Full Name DDB1 and CUL4 associated factor 6
Gene Alias NRIP; ARCAP; IQWD1; PC326; MSTP055; 1200006M05Rik
Transcripts ENSG00000143164
Virus HIV
Gene Type protein coding
HPA Location Info Focal adhesion sites;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID Q58WW2
HGNC ID HGNC:30002
VEGA ID OTTHUMG00000034572
OMIM ID 610494
String ID 9606.ENSP00000356814
PharmGKB ID PA165751150
Target gene [DCAF6] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000971 chr1 207 11 19 237 View
4009193 chr1 10 2 12 View
4009998 chr1 9 1 10 View
4012043 chr1 3 2 5 View
4013411 chr1 1 2 3 View
4014117 chr1 1 1 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of DCAF6 expression and immune infiltrating cell level correlation result in HIV+ samples
DCAF6 expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of DCAF6 expression and immune infiltrating cell level correlation result in HIV+ samples
DCAF6 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).