HTLV1 Target gene Detail Information

> DCAF17 Gene Search Result

Gene Information

Gene Name	DCAF17
Gene ID	80067
Gene Full Name	DDB1 and CUL4 associated factor 17
Gene Alias	C2orf37; C20orf37
Transcripts	ENSG00000115827
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	Q5H9S7
HGNC ID	HGNC:25784
VEGA ID	OTTHUMG00000132259
OMIM ID	612515
String ID	9606.ENSP00000364404
PharmGKB ID	PA165696520

Target gene [DCAF17] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6013841	chr2	13	5		18	View
6018353	chr2	3	6		9	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of DCAF17 expression and immune infiltrating cell level correlation result in HTLV1+ samples
DCAF17 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).