HTLV1 Target gene Detail Information

> DAGLA Gene Search Result

Gene Information

Gene Name	DAGLA
Gene ID	747
Gene Full Name	diacylglycerol lipase alpha
Gene Alias	NSDDR; C11orf11; DAGLALPHA; DAGL(ALPHA)
Transcripts	ENSG00000134780
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted membrane proteins
Uniport_ID	Q9Y4D2
HGNC ID	HGNC:1165
VEGA ID	OTTHUMG00000168160
OMIM ID	614015
String ID	9606.ENSP00000257215
Drugbank ID	BE0009164; BE0009155
PharmGKB ID	PA162383158

Target gene [DAGLA] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000853	chr11	20	525	244	789	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of DAGLA expression and immune infiltrating cell level correlation result in HTLV1+ samples
DAGLA expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of DAGLA expression and immune infiltrating cell level correlation result in HTLV1+ samples
DAGLA expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).