HBV Target gene Detail Information

> DACH1 Gene Search Result


Gene Information
Gene Name DACH1
Gene ID 1602
Gene Full Name dachshund family transcription factor 1
Gene Alias DACH
Transcripts ENSG00000276644
Virus HBV
Gene Type protein coding
HPA Location Info Nucleoplasm;Golgi apparatus;
HPA Protein Class Info Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID Q9UI36
HGNC ID HGNC:2663
VEGA ID OTTHUMG00000017063
OMIM ID 603803
String ID 9606.ENSP00000482245
PharmGKB ID PA27134
Target gene [DACH1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1010482 chr13 5 5 2 12 View
1014130 chr13 2 1 1 4 View
1018764 chr13 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of DACH1 expression and immune infiltrating cell level correlation result in HBV+ samples
DACH1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).