HTLV1 Target gene Detail Information

> CYP4V2 Gene Search Result

Gene Information

Gene Name	CYP4V2
Gene ID	285440
Gene Full Name	cytochrome P450 family 4 subfamily V member 2
Gene Alias	BCD; CYP4AH1
Transcripts	ENSG00000145476
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Nuclear speckles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted membrane proteins
Uniport_ID	Q6ZWL3
HGNC ID	HGNC:23198
VEGA ID	OTTHUMG00000160379
OMIM ID	608614
String ID	9606.ENSP00000368079
PharmGKB ID	PA134912942

Target gene [CYP4V2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6013249	chr4	20			20	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of CYP4V2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CYP4V2 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of CYP4V2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CYP4V2 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of CYP4V2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CYP4V2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).