HIV Target gene Detail Information

> CYP4F22 Gene Search Result

Gene Information

Gene Name	CYP4F22
Gene ID	126410
Gene Full Name	cytochrome P450 family 4 subfamily F member 22
Gene Alias	LI3; ARCI5; INLNE
Transcripts	ENSG00000171954
Virus	HIV
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, Predicted membrane proteins
Uniport_ID	Q6NT55
HGNC ID	HGNC:26820
VEGA ID	OTTHUMG00000182451
OMIM ID	611495
String ID	9606.ENSP00000269703
PharmGKB ID	PA162383112

Target gene [CYP4F22] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4000482	chr19	83	187	164	434	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CYP4F22 expression and immune infiltrating cell level correlation result in HIV+ samples
CYP4F22 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CYP4F22 expression and immune infiltrating cell level correlation result in HIV+ samples
CYP4F22 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).