HBV Target gene Detail Information

> CYP4B1 Gene Search Result


Gene Information
Gene Name CYP4B1
Gene ID 1580
Gene Full Name cytochrome P450 family 4 subfamily B member 1
Gene Alias CYPIVB1; P-450HP
Transcripts ENSG00000142973
Virus HBV
Gene Type protein coding
HPA Location Info Vesicles;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID P13584
HGNC ID HGNC:2644
VEGA ID OTTHUMG00000007984
OMIM ID 124075
String ID 9606.ENSP00000360991
Drugbank ID BE0004673
PharmGKB ID PA27119
Target gene [CYP4B1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1008928 chr1 5 12 1 18 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CYP4B1 expression and immune infiltrating cell level correlation result in HBV+ samples
CYP4B1 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).