HBV Target gene Detail Information

> CYP4A11 Gene Search Result


Gene Information
Gene Name CYP4A11
Gene ID 1579
Gene Full Name cytochrome P450 family 4 subfamily A member 11
Gene Alias CP4Y; CYP4A2; CYP4AII; CYPIVA11
Transcripts ENSG00000187048
Virus HBV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Enzymes, Predicted membrane proteins
Uniport_ID Q02928
HGNC ID HGNC:2642
VEGA ID OTTHUMG00000008020
OMIM ID 601310
String ID 9606.ENSP00000311095
Drugbank ID BE0000421
PharmGKB ID PA27118
Target gene [CYP4A11] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1005049 chr1 63 63 View
1017391 chr1 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CYP4A11 expression and immune infiltrating cell level correlation result in HBV+ samples
CYP4A11 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).