HBV Target gene Detail Information

> CYP3A5 Gene Search Result

Gene Information

Gene Name	CYP3A5
Gene ID	1577
Gene Full Name	cytochrome P450 family 3 subfamily A member 5
Gene Alias	CP35; PCN3; CYPIIIA5; P450PCN3
Transcripts	ENSG00000106258
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cytosol;Vesicles;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P20815
HGNC ID	HGNC:2638
VEGA ID	OTTHUMG00000156724
OMIM ID	605325
String ID	9606.ENSP00000222982
Drugbank ID	BE0002362
PharmGKB ID	PA131
FDA Approved Drug	Prasugrel

Target gene [CYP3A5] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005892	chr7	32	8	6	46	View
1005961	chr7	37	3	5	45	View
1011553	chr7	9			9	View
1013608	chr7	4	1		5	View
1404306	chr7	28	5	11	44	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CYP3A5 expression and immune infiltrating cell level correlation result in HBV+ samples
CYP3A5 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).