|
Gene Information
|
Gene Name
|
CYP3A4 |
|
Gene ID
|
1576
|
|
Gene Full Name
|
cytochrome P450 family 3 subfamily A member 4 |
|
Gene Alias
|
HLP; CP33; CP34; CYP3A; NF-25; CYP3A3; P450C3; CYPIIIA3; CYPIIIA4; P450PCN1 |
|
Transcripts
|
ENSG00000160868
|
|
Virus
|
HBV |
|
Gene Type
|
protein coding |
|
HPA Location Info
|
Cytosol;Vesicles; 
|
|
Membrane Info
|
Predicted membrane proteins |
|
HPA Protein Class Info
|
Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins |
|
Uniport_ID
|
P08684
|
|
HGNC ID
|
HGNC:2637
|
|
VEGA ID
|
OTTHUMG00000156651
|
|
OMIM ID
|
124010 |
|
String ID
|
9606.ENSP00000337915
|
|
Drugbank ID
|
BE0002638
|
|
Drug (Cytoscape Annotation)
|
Aprepitant;Tamoxifen Citrate |
|
PharmGKB ID
|
PA130
|
Target gene [CYP3A4] related to VISs 
| DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
| 1004644 |
chr7 |
18 |
15 |
41 |
74 |
View |
| 1010530 |
chr7 |
11 |
1 |
|
12 |
View |
| 1014734 |
chr7 |
3 |
|
|
3 |
View |
Relationship between gene expression and immune infiltrating cell level
| Data ID |
Disease |
Sample number |
Sample type |
|
LIHC (TCGA) |
Liver hepatocellular carcinoma |
424 |
Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18) |
> Dataset: LIHC
|
|
HeatMap of cell type fractions in all samples
|
Lollipop of CYP3A4 expression and immune infiltrating cell level correlation result in HBV+ samples
|
CYP3A4 expression: Low -> High
|
|
|
|
|
HBV Target gene Detail Information