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HBV Target gene Detail Information

> CYP2C9 Gene Search Result


Gene Information
Gene Name CYP2C9
Gene ID 1559
Gene Full Name cytochrome P450 family 2 subfamily C member 9
Gene Alias CPC9; CYP2C; CYP2C10; CYPIIC9; P450IIC9
Transcripts ENSG00000138109
Virus HBV
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Enzymes, Predicted intracellular proteins
Uniport_ID P11712
HGNC ID HGNC:2623
VEGA ID OTTHUMG00000018805
OMIM ID 601130
String ID 9606.ENSP00000260682
Drugbank ID BE0002793
PharmGKB ID PA126
FDA Approved Drug Avatrombopag;Celecoxib;Dronabinol;Erdafitinib;Flibanserin;Flurbiprofen;Lesinurad;Meloxicam;Ospemifene;Phenytoin;Piroxicam;Prasugrel;Rimegepant;Siponimod;Warfarin
Target gene [CYP2C9] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1009989 chr10 13 1 14 View
1014557 chr10 3 3 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CYP2C9 expression and immune infiltrating cell level correlation result in HBV+ samples
CYP2C9 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).