HIV Target gene Detail Information

> CYP19A1 Gene Search Result

Gene Information

Gene Name	CYP19A1
Gene ID	1588
Gene Full Name	cytochrome P450 family 19 subfamily A member 1
Gene Alias	ARO; ARO1; CPV1; CYAR; CYP19; CYPXIX; P-450AROM
Transcripts	ENSG00000137869
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	P11511
HGNC ID	HGNC:2594
VEGA ID	OTTHUMG00000131747
OMIM ID	107910
String ID	9606.ENSP00000379683
Drugbank ID	BE0002090
PharmGKB ID	PA27091

Target gene [CYP19A1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4007750	chr15	15	3		18	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CYP19A1 expression and immune infiltrating cell level correlation result in HIV+ samples
CYP19A1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).