HIV Target gene Detail Information

> CYFIP2 Gene Search Result

Gene Information

Gene Name	CYFIP2
Gene ID	26999
Gene Full Name	cytoplasmic FMR1 interacting protein 2
Gene Alias	EIEE65; PIR121
Transcripts	ENSG00000055163
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;Cytosol;Plasma membrane;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q96F07
HGNC ID	HGNC:13760
VEGA ID	OTTHUMG00000163484
OMIM ID	606323
String ID	9606.ENSP00000444645
PharmGKB ID	PA38368

Target gene [CYFIP2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4006464	chr5	5	20		25	View
4012502	chr5	3	2		5	View
4012766	chr5	1	3		4	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CYFIP2 expression and immune infiltrating cell level correlation result in HIV+ samples
CYFIP2 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CYFIP2 expression and immune infiltrating cell level correlation result in HIV+ samples
CYFIP2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).