HIV Target gene Detail Information

> CYB5B Gene Search Result

Gene Information

Gene Name	CYB5B
Gene ID	80777
Gene Full Name	cytochrome b5 type B
Gene Alias	OMB5; CYB5-M; CYPB5M
Transcripts	ENSG00000103018
Virus	HIV
Gene Type	protein coding
HPA Location Info	Endoplasmic reticulum;Centriolar satellite;Cytosol;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	O43169
HGNC ID	HGNC:24374
VEGA ID	OTTHUMG00000133020
OMIM ID	611964
String ID	9606.ENSP00000308430
Drugbank ID	BE0004474
PharmGKB ID	PA143485445

Target gene [CYB5B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004635	chr16	33	7	1	41	View
4005881	chr16	10	19		29	View
4007192	chr16	8	12		20	View
4007609	chr16	6	12		18	View
4008337	chr16	7	8		15	View
4009926	chr16	9		1	10	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CYB5B expression and immune infiltrating cell level correlation result in HIV+ samples
CYB5B expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CYB5B expression and immune infiltrating cell level correlation result in HIV+ samples
CYB5B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).