HPV Target gene Detail Information

> CXorf58 Gene Search Result

Gene Information

Gene Name	CXorf58
Gene ID	254158
Gene Full Name	chromosome X open reading frame 58
Transcripts	ENSG00000165182
Virus	HPV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Predicted intracellular proteins
Uniport_ID	Q96LI9
HGNC ID	HGNC:26356
VEGA ID	OTTHUMG00000021258
String ID	9606.ENSP00000368511
PharmGKB ID	PA145149060

Target gene [CXorf58] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
5402807	chrX				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55546 (GEO)	Oropharyngeal squamous cell carcinoma	16	Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55542 (GEO)	Oropharyngeal squamous cell carcinoma	36	Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
HNSC (TCGA)	Head and Neck squamous cell carcinoma	566	Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE55546
HeatMap of cell type fractions in all samples	Lollipop of CXorf58 expression and immune infiltrating cell level correlation result in HPV+ samples
CXorf58 expression: Low -> High

> Dataset: GSE55542
HeatMap of cell type fractions in all samples	Lollipop of CXorf58 expression and immune infiltrating cell level correlation result in HPV+ samples
CXorf58 expression: Low -> High

> Dataset: HNSC
HeatMap of cell type fractions in all samples	Lollipop of CXorf58 expression and immune infiltrating cell level correlation result in HPV+ samples
CXorf58 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).