HBV Target gene Detail Information

> CXCL3 Gene Search Result

Gene Information

Gene Name	CXCL3
Gene ID	2921
Gene Full Name	C-X-C motif chemokine ligand 3
Gene Alias	GRO3; GROg; MIP2B; SCYB3; MIP-2b; CINC-2b
Transcripts	ENSG00000163734
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Plasma proteins, Predicted secreted proteins
Gene Function	Oncogene
Uniport_ID	P19876
HGNC ID	HGNC:4604
VEGA ID	OTTHUMG00000160861
OMIM ID	139111
String ID	9606.ENSP00000296026
PharmGKB ID	PA35052

Target gene [CXCL3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1012365	chr4	1	6		7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CXCL3 expression and immune infiltrating cell level correlation result in HBV+ samples
CXCL3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).