Home
Virus
Gene
Disease
Dataset
Download
Help
 
HTLV1 Target gene Detail Information

> CXCL12 Gene Search Result


Gene Information
Gene Name CXCL12
Gene ID 6387
Gene Full Name C-X-C motif chemokine ligand 12
Gene Alias IRH; PBSF; SDF1; TLSF; TPAR1; SCYB12
Transcripts ENSG00000107562
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Predicted secreted proteins
Gene Function Suppressor gene
Uniport_ID P48061
HGNC ID HGNC:10672
VEGA ID OTTHUMG00000018054
OMIM ID 600835
String ID 9606.ENSP00000379140
Drugbank ID BE0001150
PharmGKB ID PA35602
Target gene [CXCL12] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6018320 chr10 8 1 9 View
6022224 chr10 3 2 5 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of CXCL12 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CXCL12 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of CXCL12 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CXCL12 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of CXCL12 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CXCL12 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).