HBV Target gene Detail Information

> CX3CR1 Gene Search Result

Gene Information

Gene Name	CX3CR1
Gene ID	1524
Gene Full Name	C-X3-C motif chemokine receptor 1
Gene Alias	V28; CCRL1; GPR13; CMKDR1; GPRV28; CMKBRL1
Transcripts	ENSG00000168329
Virus	HBV
Gene Type	protein coding
HPA Location Info	Plasma membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Disease related genes, G-protein coupled receptors, Plasma proteins, Potential drug targets, Predicted membrane proteins
Uniport_ID	P49238
HGNC ID	HGNC:2558
VEGA ID	OTTHUMG00000156249
OMIM ID	601470
String ID	9606.ENSP00000351059
PharmGKB ID	PA27054

Target gene [CX3CR1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1010033	chr3	10	3		13	View
1402906	chr3	10	3		13	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CX3CR1 expression and immune infiltrating cell level correlation result in HBV+ samples
CX3CR1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).