HIV Target gene Detail Information

> CWC27 Gene Search Result

Gene Information

Gene Name	CWC27
Gene ID	10283
Gene Full Name	CWC27 spliceosome associated protein homolog
Gene Alias	RPSKA; NY-CO-10; SDCCAG10; SDCCAG-10
Transcripts	ENSG00000153015
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins
Uniport_ID	Q6UX04
HGNC ID	HGNC:10664
VEGA ID	OTTHUMG00000074069
OMIM ID	617170
String ID	9606.ENSP00000370460
PharmGKB ID	PA35594

Target gene [CWC27] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4013714	chr5	2	1		3	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CWC27 expression and immune infiltrating cell level correlation result in HIV+ samples
CWC27 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).