HBV Target gene Detail Information

> CTNNA1 Gene Search Result

Gene Information

Gene Name	CTNNA1
Gene ID	1495
Gene Full Name	catenin alpha 1
Gene Alias	MDPT2; CAP102
Transcripts	ENSG00000044115
Virus	HBV
Gene Type	protein coding
HPA Location Info	Cell Junctions;Plasma membrane;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P35221
HGNC ID	HGNC:2509
VEGA ID	OTTHUMG00000163502
OMIM ID	116805
String ID	9606.ENSP00000304669
PharmGKB ID	PA27008

Target gene [CTNNA1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1005763	chr5	44	2	2	48	View
1005816	chr5	43	2	2	47	View
1007269	chr5	24	4		28	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CTNNA1 expression and immune infiltrating cell level correlation result in HBV+ samples
CTNNA1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).