Home
Virus
Gene
Disease
Dataset
Download
Help
 
HIV Target gene Detail Information

> CTCF Gene Search Result


Gene Information
Gene Name CTCF
Gene ID 10664
Gene Full Name CCCTC-binding factor
Gene Alias MRD21
Transcripts ENSG00000102974
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;
HPA Protein Class Info Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors
Gene Function Suppressor gene
Uniport_ID P49711
HGNC ID HGNC:13723
VEGA ID OTTHUMG00000137539
OMIM ID 604167
String ID 9606.ENSP00000264010
PharmGKB ID PA26998
Target gene [CTCF] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4002711 chr16 82 1 83 View
4002776 chr16 63 16 1 80 View
4002785 chr16 42 20 18 80 View
4004303 chr16 36 10 46 View
4004852 chr16 28 10 38 View
4005063 chr16 28 8 36 View
4005697 chr16 26 4 30 View
4007425 chr16 16 3 19 View
4008003 chr16 11 4 2 17 View
4009376 chr16 12 12 View
4009821 chr16 8 2 10 View
4010293 chr16 9 9 View
4010403 chr16 7 2 9 View
4011131 chr16 5 2 7 View
4014816 chr16 2 2 View
4015623 chr16 1 1 View
4016238 chr16 0 View
4300039 chr16 55 24 79 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of CTCF expression and immune infiltrating cell level correlation result in HIV+ samples
CTCF expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of CTCF expression and immune infiltrating cell level correlation result in HIV+ samples
CTCF expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).