HPV Target gene Detail Information

> CT45A6 Gene Search Result


Gene Information
Gene Name CT45A6
Gene ID 541465
Gene Full Name cancer/testis antigen family 45 member A6
Gene Alias CT45-5; CT45-6; CT45.6; CT45A5; CT45A7
Transcripts ENSG00000278289
Virus HPV
Gene Type protein coding
HPA Location Info Nucleoli;Nucleoplasm;
HPA Protein Class Info Predicted intracellular proteins
Uniport_ID P0DMU7
HGNC ID HGNC:33271
VEGA ID OTTHUMG00000188604
OMIM ID 300797
PharmGKB ID PA164718204
Target gene [CT45A6] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5003911 chrX 1 1 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of CT45A6 expression and immune infiltrating cell level correlation result in HPV+ samples
CT45A6 expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of CT45A6 expression and immune infiltrating cell level correlation result in HPV+ samples
CT45A6 expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of CT45A6 expression and immune infiltrating cell level correlation result in HPV+ samples
CT45A6 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).