HIV Target gene Detail Information

> CSNK1A1 Gene Search Result

Gene Information

Gene Name	CSNK1A1
Gene ID	1452
Gene Full Name	casein kinase 1 alpha 1
Gene Alias	CK1; CK1a; CKIa; HLCDGP1; PRO2975; HEL-S-77p
Transcripts	ENSG00000113712
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;
HPA Protein Class Info	Enzymes, Plasma proteins, Predicted intracellular proteins
Gene Function	Suppressor gene
Uniport_ID	P48729
HGNC ID	HGNC:2451
VEGA ID	OTTHUMG00000163463
OMIM ID	600505
String ID	9606.ENSP00000421689
Drugbank ID	BE0009381
PharmGKB ID	PA26951

Target gene [CSNK1A1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4008906	chr5	8	5		13	View
4016384	chr5				0	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CSNK1A1 expression and immune infiltrating cell level correlation result in HIV+ samples
CSNK1A1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CSNK1A1 expression and immune infiltrating cell level correlation result in HIV+ samples
CSNK1A1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).