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HPV Target gene Detail Information

> CSF3R Gene Search Result


Gene Information
Gene Name CSF3R
Gene ID 1441
Gene Full Name colony stimulating factor 3 receptor
Gene Alias SCN7; CD114; GCSFR
Transcripts ENSG00000119535
Virus HPV
Gene Type protein coding
HPA Location Info
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins
Gene Function Oncogene
Uniport_ID Q99062
HGNC ID HGNC:2439
VEGA ID OTTHUMG00000008010
OMIM ID 138971
String ID 9606.ENSP00000362195
Drugbank ID BE0000793
PharmGKB ID PA26942
Target gene [CSF3R] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
5403414 chr1 3 1 1 5 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE140662 (GEO) Condyloma Acuminatum 8 Condyloma acuminata (HPV+)(5), Skin(3)
GSE65858 (GEO) Head and neck squamous cell carcinoma 270 Head and neck squamous cell carcinoma (EBV+)(73), Head and neck squamous cell carcinoma (EBV-)(197)
GSE40774 (GEO) Head and neck squamous cell carcinoma 134 Head and neck Squamous cell carcinomas GLOTTIC LARYNX (EBV-)(2), Head and neck Squamous cell carcinomas HYPOPHARYNX (EBV-)(9), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV-)(23), Head and neck Squamous cell carcinomas ORAL CAVITY (EBV+)(2), Head and neck Squamous cell carcinomas OROPHARYNX (EBV-)(22), Head and neck Squamous cell carcinomas OROPHARYNX (EBV+)(54), Head and neck Squamous cell carcinomas OTHER (EBV+)(1), Head and neck Squamous cell carcinomas SUBGLOTTIC LARYNX (EBV-)(1), Head and neck Squamous cell carcinomas SUPRAGLOTTIC (EBV-)(19), Squamous cell carcinomas SUPRAGLOTTIC (EBV+)(1)
GSE55546 (GEO) Oropharyngeal squamous cell carcinoma 16 Oropharyngeal cancers (HPV+)(12), Normal (4)
GSE55544 (GEO) Oropharyngeal squamous cell carcinoma 23 Oropharyngeal cancers HPV Active (11), Oropharyngeal cancers HPV Inactive (4), Oropharyngeal cancers HPV Negative (8)
GSE55542 (GEO) Oropharyngeal squamous cell carcinoma 36 Oropharyngeal cancers HPV Active (12), Oropharyngeal cancers HPV Inactive (8), Oropharyngeal cancers HPV Negative (16)
GSE51993 (GEO) Cervical intraepithelial neoplasia 24 Cervical intraepithelial neoplasia (HPV+)(17), Normal(7)
HNSC (TCGA) Head and Neck squamous cell carcinoma 566 Head and Neck squamous cell carcinoma(HPV-)(483),Head and Neck squamous cell carcinoma(HPV+)(39),Paracancerous(HPV-)(44)

> Dataset: GSE140662

HeatMap of cell type fractions in all samples Lollipop of CSF3R expression and immune infiltrating cell level correlation result in HPV+ samples
CSF3R expression: Low -> High

> Dataset: GSE65858

HeatMap of cell type fractions in all samples Lollipop of CSF3R expression and immune infiltrating cell level correlation result in HPV+ samples
CSF3R expression: Low -> High

> Dataset: GSE40774

HeatMap of cell type fractions in all samples Lollipop of CSF3R expression and immune infiltrating cell level correlation result in HPV+ samples
CSF3R expression: Low -> High

> Dataset: GSE55546

HeatMap of cell type fractions in all samples Lollipop of CSF3R expression and immune infiltrating cell level correlation result in HPV+ samples
CSF3R expression: Low -> High

> Dataset: GSE55544

HeatMap of cell type fractions in all samples Lollipop of CSF3R expression and immune infiltrating cell level correlation result in HPV+ samples
CSF3R expression: Low -> High

> Dataset: GSE55542

HeatMap of cell type fractions in all samples Lollipop of CSF3R expression and immune infiltrating cell level correlation result in HPV+ samples
CSF3R expression: Low -> High

> Dataset: GSE51993

HeatMap of cell type fractions in all samples Lollipop of CSF3R expression and immune infiltrating cell level correlation result in HPV+ samples
CSF3R expression: Low -> High

> Dataset: HNSC

HeatMap of cell type fractions in all samples Lollipop of CSF3R expression and immune infiltrating cell level correlation result in HPV+ samples
CSF3R expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).