HBV Target gene Detail Information

> CSF1R Gene Search Result


Gene Information
Gene Name CSF1R
Gene ID 1436
Gene Full Name colony stimulating factor 1 receptor
Gene Alias FMS; CSFR; FIM2; HDLS; C-FMS; CD115; CSF-1R; M-CSF-R
Transcripts ENSG00000182578
Virus HBV
Gene Type protein coding
HPA Location Info Plasma membrane;Vesicles;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins
Gene Function Oncogene
Uniport_ID P07333
HGNC ID HGNC:2433
VEGA ID OTTHUMG00000130050
OMIM ID 164770
String ID 9606.ENSP00000286301
Drugbank ID BE0000853
Drug (Cytoscape Annotation) Dasatinib;Nilotinib;Imatinib Mesylate;Pazopanib Hydrochloride;Bosutinib;Sorafenib Tosylate;Sunitinib Malate;Crizotinib;Axitinib
PharmGKB ID PA26936
FDA Approved Drug Pexidartinib
Target gene [CSF1R] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
1016116 chr5 2 2 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
LIHC (TCGA) Liver hepatocellular carcinoma 424 Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC

HeatMap of cell type fractions in all samples Lollipop of CSF1R expression and immune infiltrating cell level correlation result in HBV+ samples
CSF1R expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).