Gene Information
Gene Name
|
CSF1R |
Gene ID
|
1436
|
Gene Full Name
|
colony stimulating factor 1 receptor |
Gene Alias
|
FMS; CSFR; FIM2; HDLS; C-FMS; CD115; CSF-1R; M-CSF-R |
Transcripts
|
ENSG00000182578
|
Virus
|
HBV |
Gene Type
|
protein coding |
HPA Location Info
|
Plasma membrane;Vesicles;
|
Membrane Info
|
Predicted membrane proteins |
HPA Protein Class Info
|
Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins |
Gene Function
|
Oncogene
|
Uniport_ID
|
P07333
|
HGNC ID
|
HGNC:2433
|
VEGA ID
|
OTTHUMG00000130050
|
OMIM ID
|
164770 |
String ID
|
9606.ENSP00000286301
|
Drugbank ID
|
BE0000853
|
Drug (Cytoscape Annotation)
|
Dasatinib;Nilotinib;Imatinib Mesylate;Pazopanib Hydrochloride;Bosutinib;Sorafenib Tosylate;Sunitinib Malate;Crizotinib;Axitinib |
PharmGKB ID
|
PA26936
|
FDA Approved Drug
|
Pexidartinib |
Target gene [CSF1R] related to VISs
DVID |
Chromosome |
HM |
TFBS |
CA |
Sum of Overlapped Records |
Detail |
1016116 |
chr5 |
2 |
|
|
2 |
View |
Relationship between gene expression and immune infiltrating cell level
Data ID |
Disease |
Sample number |
Sample type |
LIHC (TCGA) |
Liver hepatocellular carcinoma |
424 |
Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18) |
> Dataset: LIHC
|
HeatMap of cell type fractions in all samples
|
Lollipop of CSF1R expression and immune infiltrating cell level correlation result in HBV+ samples
|
CSF1R expression: Low -> High
|
|
|
|
|