HIV Target gene Detail Information

> CSE1L Gene Search Result

Gene Information

Gene Name	CSE1L
Gene ID	1434
Gene Full Name	chromosome segregation 1 like
Gene Alias	CAS; CSE1; XPO2
Transcripts	ENSG00000124207
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Cytosol;
HPA Protein Class Info	Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters
Uniport_ID	P55060
HGNC ID	HGNC:2431
VEGA ID	OTTHUMG00000033046
OMIM ID	601342
String ID	9606.ENSP00000262982
PharmGKB ID	PA26933

Target gene [CSE1L] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004868	chr20	36	2		38	View
4008738	chr20	1	13		14	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CSE1L expression and immune infiltrating cell level correlation result in HIV+ samples
CSE1L expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CSE1L expression and immune infiltrating cell level correlation result in HIV+ samples
CSE1L expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).