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HTLV1 Target gene Detail Information

> CRNKL1 Gene Search Result


Gene Information
Gene Name CRNKL1
Gene ID 51340
Gene Full Name crooked neck pre-mRNA splicing factor 1
Gene Alias CLF; CRN; Clf1; HCRN; SYF3; MSTP021
Transcripts ENSG00000101343
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Plasma proteins, Predicted intracellular proteins
Uniport_ID Q9BZJ0
HGNC ID HGNC:15762
VEGA ID OTTHUMG00000032000
OMIM ID 610952
String ID 9606.ENSP00000366557
PharmGKB ID PA26886
Target gene [CRNKL1] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6010953 chr20 28 28 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of CRNKL1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CRNKL1 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of CRNKL1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CRNKL1 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of CRNKL1 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CRNKL1 expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).