HIV Target gene Detail Information

> CRLF3 Gene Search Result

Gene Information

Gene Name	CRLF3
Gene ID	51379
Gene Full Name	cytokine receptor like factor 3
Gene Alias	FRWS; CRLM9; p48.2; CREME9; CYTOR4; CREME-9
Transcripts	ENSG00000176390
Virus	HIV
Gene Type	protein coding
HPA Location Info	Cytosol;Plasma membrane;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q8IUI8
HGNC ID	HGNC:17177
VEGA ID	OTTHUMG00000179005
OMIM ID	614853
String ID	9606.ENSP00000318804
PharmGKB ID	PA26884

Target gene [CRLF3] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4004370	chr17	20	25		45	View
4009233	chr17	12			12	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CRLF3 expression and immune infiltrating cell level correlation result in HIV+ samples
CRLF3 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CRLF3 expression and immune infiltrating cell level correlation result in HIV+ samples
CRLF3 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).