HIV Target gene Detail Information

> CREM Gene Search Result

Gene Information

Gene Name	CREM
Gene ID	1390
Gene Full Name	cAMP responsive element modulator
Gene Alias	ICER; CREM-2; hCREM-2
Transcripts	ENSG00000095794
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nucleoplasm;Vesicles;
HPA Protein Class Info	Predicted intracellular proteins, Transcription factors
Gene Function	Suppressor gene
Uniport_ID	Q03060
HGNC ID	HGNC:2352
VEGA ID	OTTHUMG00000017953
OMIM ID	123812
String ID	9606.ENSP00000265372
PharmGKB ID	PA26871

Target gene [CREM] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4010662	chr10	7	1		8	View
4011172	chr10	6	1		7	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CREM expression and immune infiltrating cell level correlation result in HIV+ samples
CREM expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).