HIV Target gene Detail Information

> CREBBP Gene Search Result


Gene Information
Gene Name CREBBP
Gene ID 1387
Gene Full Name CREB binding protein
Gene Alias CBP; RSTS; KAT3A; RSTS1
Transcripts ENSG00000005339
Virus HIV
Gene Type protein coding
HPA Location Info Nucleoplasm;Nuclear bodies;
HPA Protein Class Info Cancer-related genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins
Gene Function Suppressor gene
Uniport_ID Q92793
HGNC ID HGNC:2348
VEGA ID OTTHUMG00000129431
OMIM ID 600140
String ID 9606.ENSP00000262367
Drugbank ID BE0004367
PharmGKB ID PA26866
Target gene [CREBBP] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4000151 chr16 61 387 424 872 View
4000170 chr16 99 381 348 828 View
4000171 chr16 99 381 348 828 View
4000275 chr16 123 154 327 604 View
4000454 chr16 43 325 84 452 View
4000644 chr16 134 139 61 334 View
4001048 chr16 196 19 10 225 View
4001093 chr16 62 46 108 216 View
4001120 chr16 163 45 3 211 View
4001757 chr16 134 134 View
4002189 chr16 105 1 1 107 View
4002205 chr16 12 87 7 106 View
4002239 chr16 25 63 15 103 View
4002729 chr16 34 37 11 82 View
4004114 chr16 5 40 4 49 View
4004650 chr16 26 7 8 41 View
4004734 chr16 35 1 4 40 View
4005417 chr16 20 5 8 33 View
4007441 chr16 15 4 19 View
4009652 chr16 7 4 11 View
4010492 chr16 1 7 1 9 View
4010950 chr16 1 6 1 8 View
4010951 chr16 1 6 1 8 View
4010952 chr16 1 6 1 8 View
4011574 chr16 6 6 View
4012068 chr16 5 5 View
4012901 chr16 4 4 View
4013096 chr16 4 4 View
4013794 chr16 2 1 3 View
4013865 chr16 2 1 3 View
4013866 chr16 1 2 3 View
4013867 chr16 3 3 View
4014385 chr16 2 2 View
4015047 chr16 1 1 View
4015291 chr16 1 1 View
4015516 chr16 1 1 View
4015620 chr16 1 1 View
4016230 chr16 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO) HIV-infected disease 44 HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of CREBBP expression and immune infiltrating cell level correlation result in HIV+ samples
CREBBP expression: Low -> High

> Dataset: GSE50834

HeatMap of cell type fractions in all samples Lollipop of CREBBP expression and immune infiltrating cell level correlation result in HIV+ samples
CREBBP expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).