HTLV1 Target gene Detail Information

> CREB3L2 Gene Search Result


Gene Information
Gene Name CREB3L2
Gene ID 64764
Gene Full Name cAMP responsive element binding protein 3 like 2
Gene Alias BBF2H7
Transcripts ENSG00000182158
Virus HTLV1
Gene Type protein coding
HPA Location Info Endoplasmic reticulum;Nucleoplasm;
Membrane Info Predicted membrane proteins
HPA Protein Class Info Cancer-related genes, Disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors
Uniport_ID Q70SY1
HGNC ID HGNC:23720
VEGA ID OTTHUMG00000155744
OMIM ID 608834
String ID 9606.ENSP00000329140
PharmGKB ID PA134914841
Target gene [CREB3L2] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000239 chr7 2470 153 38 2661 View
6000848 chr7 636 31 126 793 View
6004073 chr7 125 5 130 View
6011493 chr7 25 1 26 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of CREB3L2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CREB3L2 expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of CREB3L2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CREB3L2 expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of CREB3L2 expression and immune infiltrating cell level correlation result in HTLV1+ samples
CREB3L2 expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).