HIV Target gene Detail Information

> CPNE1 Gene Search Result

Gene Information

Gene Name	CPNE1
Gene ID	8904
Gene Full Name	copine 1
Gene Alias	CPN1; COPN1
Transcripts	ENSG00000214078
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear membrane;Nucleoplasm;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q99829
HGNC ID	HGNC:2314
VEGA ID	OTTHUMG00000032356
OMIM ID	604205
String ID	9606.ENSP00000317257
Drugbank ID	BE0008927
PharmGKB ID	PA26831

Target gene [CPNE1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003665	chr20	49	6	2	57	View
4004895	chr20	34	3	1	38	View
4006830	chr20	18	4		22	View
4010917	chr20	8			8	View
4012295	chr20	5			5	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CPNE1 expression and immune infiltrating cell level correlation result in HIV+ samples
CPNE1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CPNE1 expression and immune infiltrating cell level correlation result in HIV+ samples
CPNE1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).