HIV Target gene Detail Information

> CPE Gene Search Result


Gene Information
Gene Name CPE
Gene ID 1363
Gene Full Name carboxypeptidase E
Gene Alias CPH
Transcripts ENSG00000109472
Virus HIV
Gene Type protein coding
HPA Location Info Centrosome;Nucleoplasm;Vesicles;
HPA Protein Class Info Enzymes, Plasma proteins, Predicted intracellular proteins
Uniport_ID P16870
HGNC ID HGNC:2303
VEGA ID OTTHUMG00000150252
OMIM ID 114855
String ID 9606.ENSP00000386104
Drugbank ID BE0001123
PharmGKB ID PA26824
Target gene [CPE] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
4006283 chr4 11 13 2 26 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE17372 (GEO) AIDS-associated lymphoma 17 AIDS-Related Lymphomas (HIV+)(17)

> Dataset: GSE17372

HeatMap of cell type fractions in all samples Lollipop of CPE expression and immune infiltrating cell level correlation result in HIV+ samples
CPE expression: Low -> High

Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).