HIV Target gene Detail Information

> CPD Gene Search Result

Gene Information

Gene Name	CPD
Gene ID	1362
Gene Full Name	carboxypeptidase D
Gene Alias	GP180
Transcripts	ENSG00000108582
Virus	HIV
Gene Type	protein coding
HPA Location Info	Nuclear speckles;Nucleoplasm;Nuclear membrane;
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Enzymes, Predicted intracellular proteins, Predicted membrane proteins
Uniport_ID	O75976
HGNC ID	HGNC:2301
VEGA ID	OTTHUMG00000132797
OMIM ID	603102
String ID	9606.ENSP00000225719
Drugbank ID	BE0004568
PharmGKB ID	PA26823

Target gene [CPD] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4002844	chr17	68	9		77	View
4008939	chr17	6	6	1	13	View
4009378	chr17	9	3		12	View
4015304	chr17	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of CPD expression and immune infiltrating cell level correlation result in HIV+ samples
CPD expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of CPD expression and immune infiltrating cell level correlation result in HIV+ samples
CPD expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).