HBV Target gene Detail Information

> CPB2 Gene Search Result

Gene Information

Gene Name	CPB2
Gene ID	1361
Gene Full Name	carboxypeptidase B2
Gene Alias	CPU; PCPB; TAFI
Transcripts	ENSG00000080618
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Enzymes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins
Uniport_ID	Q96IY4
HGNC ID	HGNC:2300
VEGA ID	OTTHUMG00000016867
OMIM ID	603101
String ID	9606.ENSP00000181383
Drugbank ID	BE0003407
PharmGKB ID	PA26822

Target gene [CPB2] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1404507	chr13	51	34	17	102	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CPB2 expression and immune infiltrating cell level correlation result in HBV+ samples
CPB2 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).