HBV Target gene Detail Information

> CPA6 Gene Search Result

Gene Information

Gene Name	CPA6
Gene ID	57094
Gene Full Name	carboxypeptidase A6
Gene Alias	CPAH; ETL5; FEB11
Transcripts	ENSG00000165078
Virus	HBV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Enzymes, Potential drug targets, Predicted secreted proteins
Uniport_ID	Q8N4T0
HGNC ID	HGNC:17245
VEGA ID	OTTHUMG00000164575
OMIM ID	609562
String ID	9606.ENSP00000297770
Drugbank ID	BE0010415; BE0009992
PharmGKB ID	PA38444

Target gene [CPA6] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
1006163	chr8	30	11	1	42	View
1008790	chr8	9		10	19	View
1016572	chr8	1			1	View
1016575	chr8	1			1	View
1017200	chr8	1			1	View
1017498	chr8	1			1	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
LIHC (TCGA)	Liver hepatocellular carcinoma	424	Liver hepatocellular carcinoma HCV (HBV+)(86), Liver hepatocellular carcinoma HCV (HBV-)(19), Liver hepatocellular carcinoma (HBV+)(209), Liver hepatocellular carcinoma (HBV+)(60), Paracancerous HCV (HBV+)(4), Paracancerous (HBV-)(28), Paracancerous (HBV+)(18)

> Dataset: LIHC
HeatMap of cell type fractions in all samples	Lollipop of CPA6 expression and immune infiltrating cell level correlation result in HBV+ samples
CPA6 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).