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HTLV1 Target gene Detail Information

> CP Gene Search Result


Gene Information
Gene Name CP
Gene ID 1356
Gene Full Name ceruloplasmin
Gene Alias CP-2
Transcripts ENSG00000047457
Virus HTLV1
Gene Type protein coding
HPA Location Info
HPA Protein Class Info Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins
Uniport_ID P00450
HGNC ID HGNC:2295
VEGA ID OTTHUMG00000159563
OMIM ID 117700
String ID 9606.ENSP00000264613
Drugbank ID BE0001140
PharmGKB ID PA26815
Target gene [CP] related to VISs
DVID Chromosome HM TFBS CA Sum of Overlapped Records Detail
6000893 chr9 287 307 146 740 View
6001395 chr7 278 124 51 453 View
6002756 chr2 11 187 13 211 View
6006501 chr2 49 16 3 68 View
6009481 chr2 34 2 36 View
6013670 chr2 9 9 18 View
6016820 chr7 8 3 11 View
6019171 chr3 3 5 8 View
6024847 chr2 2 1 3 View
6028482 chr2 1 1 View
6029030 chr2 1 1 View
6030772 chr2 0 View

Relationship between gene expression and immune infiltrating cell level
Data ID Disease Sample number Sample type
GSE55851 (GEO) Adult T-cell leukemia 21 Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO) HTLV-1 associated myelopathy 39 Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO) HTLV-1 associated myelopathy 35 Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851

HeatMap of cell type fractions in all samples Lollipop of CP expression and immune infiltrating cell level correlation result in HTLV1+ samples
CP expression: Low -> High

> Dataset: GSE29312

HeatMap of cell type fractions in all samples Lollipop of CP expression and immune infiltrating cell level correlation result in HTLV1+ samples
CP expression: Low -> High

> Dataset: GSE29332

HeatMap of cell type fractions in all samples Lollipop of CP expression and immune infiltrating cell level correlation result in HTLV1+ samples
CP expression: Low -> High
Contents
Description

Gene Information Note

  • Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

  • Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
  • Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).