HIV Target gene Detail Information

> COX6B1 Gene Search Result

Gene Information

Gene Name	COX6B1
Gene ID	1340
Gene Full Name	cytochrome c oxidase subunit 6B1
Gene Alias	COXG; COX6B; COXVIb1
Transcripts	ENSG00000126267
Virus	HIV
Gene Type	protein coding
HPA Location Info	Mitochondria;
HPA Protein Class Info	Disease related genes, Plasma proteins, Predicted intracellular proteins
Uniport_ID	P14854
HGNC ID	HGNC:2280
VEGA ID	OTTHUMG00000048112
OMIM ID	124089
String ID	9606.ENSP00000246554
Drugbank ID	BE0003995
PharmGKB ID	PA26797

Target gene [COX6B1] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4003090	chr19	50	17	3	70	View
4004974	chr19	26	11		37	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of COX6B1 expression and immune infiltrating cell level correlation result in HIV+ samples
COX6B1 expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of COX6B1 expression and immune infiltrating cell level correlation result in HIV+ samples
COX6B1 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).