HIV Target gene Detail Information

> COX5A Gene Search Result

Gene Information

Gene Name	COX5A
Gene ID	9377
Gene Full Name	cytochrome c oxidase subunit 5A
Gene Alias	VA; COX; COX-VA
Transcripts	ENSG00000178741
Virus	HIV
Gene Type	protein coding
HPA Location Info
HPA Protein Class Info	Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters
Uniport_ID	P20674
HGNC ID	HGNC:2267
VEGA ID	OTTHUMG00000142825
OMIM ID	603773
String ID	9606.ENSP00000317780
Drugbank ID	BE0003988
PharmGKB ID	PA26784

Target gene [COX5A] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
4011956	chr15	2	3	1	6	View
4014147	chr15	2			2	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE17372 (GEO)	AIDS-associated lymphoma	17	AIDS-Related Lymphomas (HIV+)(17)
GSE50834 (GEO)	HIV-infected disease	44	HIV infected (23), HIV/TB co-infected (21)

> Dataset: GSE17372
HeatMap of cell type fractions in all samples	Lollipop of COX5A expression and immune infiltrating cell level correlation result in HIV+ samples
COX5A expression: Low -> High

> Dataset: GSE50834
HeatMap of cell type fractions in all samples	Lollipop of COX5A expression and immune infiltrating cell level correlation result in HIV+ samples
COX5A expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).