HTLV1 Target gene Detail Information

> COX11 Gene Search Result

Gene Information

Gene Name	COX11
Gene ID	1353
Gene Full Name	cytochrome c oxidase copper chaperone COX11
Gene Alias	COX11P
Transcripts	ENSG00000166260
Virus	HTLV1
Gene Type	protein coding
HPA Location Info
Membrane Info	Predicted membrane proteins
HPA Protein Class Info	Predicted membrane proteins
Uniport_ID	Q9Y6N1
HGNC ID	HGNC:2261
VEGA ID	OTTHUMG00000177838
OMIM ID	603648
String ID	9606.ENSP00000299335
PharmGKB ID	PA26777

Target gene [COX11] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6000335	chr17	1807	97	157	2061	View
6001279	chr17	454	26	24	504	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of COX11 expression and immune infiltrating cell level correlation result in HTLV1+ samples
COX11 expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of COX11 expression and immune infiltrating cell level correlation result in HTLV1+ samples
COX11 expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of COX11 expression and immune infiltrating cell level correlation result in HTLV1+ samples
COX11 expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).