HTLV1 Target gene Detail Information

> CORO2B Gene Search Result

Gene Information

Gene Name	CORO2B
Gene ID	10391
Gene Full Name	coronin 2B
Gene Alias	CLIPINC
Transcripts	ENSG00000103647
Virus	HTLV1
Gene Type	protein coding
HPA Location Info	Focal adhesion sites;Plasma membrane;
HPA Protein Class Info	Plasma proteins, Predicted intracellular proteins
Uniport_ID	Q9UQ03
HGNC ID	HGNC:2256
VEGA ID	OTTHUMG00000133288
OMIM ID	605002
String ID	9606.ENSP00000454783
PharmGKB ID	PA26772

Target gene [CORO2B] related to VISs

DVID	Chromosome	HM	TFBS	CA	Sum of Overlapped Records	Detail
6009684	chr15	13	12	10	35	View

Relationship between gene expression and immune infiltrating cell level

Data ID	Disease	Sample number	Sample type
GSE55851 (GEO)	Adult T-cell leukemia	21	Normal (3), Asymptomatic carriers (HTLV1+)(6), Adult T-cell Leukemia-lymphoma (HTLV1+)(12)
GSE29312 (GEO)	HTLV-1 associated myelopathy	39	Normal (9), Asymptomatic carriers (HTLV1+)(20), HTLV-1-associated myelopathy (HTLV1+)(10)
GSE29332 (GEO)	HTLV-1 associated myelopathy	35	Normal (8), Asymptomatic carriers (HTLV1+)(17), HTLV-1-associated myelopathy (HTLV1+)(10)

> Dataset: GSE55851
HeatMap of cell type fractions in all samples	Lollipop of CORO2B expression and immune infiltrating cell level correlation result in HTLV1+ samples
CORO2B expression: Low -> High

> Dataset: GSE29312
HeatMap of cell type fractions in all samples	Lollipop of CORO2B expression and immune infiltrating cell level correlation result in HTLV1+ samples
CORO2B expression: Low -> High

> Dataset: GSE29332
HeatMap of cell type fractions in all samples	Lollipop of CORO2B expression and immune infiltrating cell level correlation result in HTLV1+ samples
CORO2B expression: Low -> High

Contents
Description

Gene Information Note

Integration Table: if previous studies reported that target gene was altered by virus integration events, the overlap between VISs in this literature and Cistrome factors was listed in the "Target gene [gene] related to VIS" section

Immune Analysis Plot Note

Left: Heatmap of target gene expression and the level of various types of immune cells (cell type fractions) in all samples based on CIBERSORT method.
Right: Correlation of target gene expression and the level of various types of immune cells in virus positive samples (Pearson Correlation Coefficient).